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HERDIN Record #: PCHRDPC011194 Submitted: 16 May 2007 Modified: 04 July 2020

Left ventricular diastolic filling doppler indices is a useful adjunct in the interpretation of dobutamine stress echocardiogram.

Grace Casaclang ,
Louwe Go ,
Marietta Crisostomo ,
Gregorio Rogelio,
Mary Ann Lao M,
Homobono Calleja

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BACKGROUND: In coronary occlusion or heart failure, abnormal relaxation of the left ventricle is the earliest manifestation.

OBJECTIVE: To measure the Doppler derived diastolic indices from baseline to peak dose dobutamine and compare patients with normal (Group I) and abnormal (Group II) wall motion

DESIGN: Case control study of patients who undergo DSE

METHODS: Doppler signals of transmitral blood flow were obtained at baseline and peak dobutamine stress The following were measured: Peak early filling velocity E - peak early left ventricular filling velocity (cm/s) Peak atrial filling velocity A -- velocity of atrial contraction (cm/s) Peak early to atrial velocity ratio (E/A) - relative contribution of early and late ventricular filling E acceleration time - rate of increase of E velocity stet (m/s2) E decceleration time - rate of stet of velocity following E velocity (m/s2) Total diastolic VTI - velocity time integral (cm) Isovolumic relaxation time (IVRT) - time from aortic valve closure to mitral valve opening (ms) Corresponding heart rate - heart rate at time Doppler indices were obtained during baseline and peak dose dobutamine.

RESULTS: Patients with normal wall motion and contractility have increased E and A velocities, faster E deceleration time and E acceleration time. The E/A ratio and VTI are unchanged. The IVRT is decreased. Patients with segmental wall motion abnormality have decreased E velocity, unchanged E deceleration time. The E acceleration time may be unchanged. The A velocity is increased. The E/A ratio and IVRT are reduced. The TI is unchanged antihypertensive was doubled.

Publication Type
Publication Sub Type
Journal Article, Original
Philippine Journal of Cardiology
Publication Date
July-September 1999
LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health Research and Development Box No. 44 Fulltext Print Format
Philippine Council for Health Research and Development Fulltext pdf (Request Document)
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